Ibuprofen is one of a group of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). They are often used to help relieve pain, reduce inflammation and reduce fevers.
Claims have circulated on social media linking the use of ibuprofen to a worsening of the symptoms of COVID-19. These claims have been made by a number of people and organisations. Claims began following a letter on March 11, 2020 in The Lancet journal, which suggested, on the basis of limited evidence, that NSAIDs increase a particular enzyme (a type of substance that occurs naturally in the body), and this increase could worsen the symptoms of COVID-19 in some people.
There is no high-quality evidence linking the use of NSAIDs, like ibuprofen, with worsening symptoms of COVID-19.
Lead Researcher: Dr. KM Saif-Ur-Rahman, Evidence Synthesis Ireland and Cochrane Ireland, University of Galway.
Reviewed by: Prof. Declan Devane, College of Medicine, Nursing and Health Sciences, HRB-Trials Methodology Research Network, Evidence Synthesis Ireland & Cochrane Ireland, University of Galway.
Topic advisor: Prof. Andrew Murphy, College of Medicine, Nursing and Health Sciences, University of Galway, Health Research Board Primary Care Clinical Trials Network Ireland and General Practitioner principal in a semi-rural setting.
Public and patient advisor: Deirdre Mac Loughlin, PPI Ignite, University of Galway.
Journalist Advisor: Dr. Claire O’Connell, Journalist, Contributor, The Irish Times.
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